Nicholas J White Selected Research

Mefloquine (Lariam)

10/2021	Arterolane-piperaquine-mefloquine versus arterolane-piperaquine and artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a single-centre, open-label, randomised, non-inferiority trial.
10/2021	A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border.
1/2020	Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
1/2019	Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study.
1/2019	Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults.
1/2016	Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors.
11/2015	Protein profiling of mefloquine resistant Plasmodium falciparum using mass spectrometry-based proteomics.
4/2014	Treatment of suspected hyper-reactive malarial splenomegaly (HMS) in pregnancy with mefloquine.
3/2013	Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.
3/2011	Plasmodium vivax recurrence following falciparum and mixed species malaria: risk factors and effect of antimalarial kinetics.

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Nicholas J White Research Topics

Disease

256	Malaria 10/2022 - 01/2002
186	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2022 - 03/2002
84	Infections 01/2022 - 02/2002
50	Vivax Malaria 10/2021 - 05/2003
25	Glucosephosphate Dehydrogenase Deficiency 06/2022 - 12/2008
24	Hemolysis 06/2022 - 04/2005
18	Parasitemia 12/2020 - 03/2002
17	Fever (Fevers) 10/2021 - 02/2002
15	Body Weight (Weight, Body) 10/2021 - 04/2005
15	Reinfection 01/2020 - 10/2004
14	Melioidosis 01/2020 - 03/2003
11	COVID-19 10/2022 - 01/2020
10	Coma (Comas) 01/2019 - 07/2003
8	Cryptococcal Meningitis 01/2021 - 09/2002
8	Typhoid Fever (Typhoid) 01/2021 - 07/2002
8	Sepsis (Septicemia) 01/2019 - 09/2003
8	Acidosis 01/2019 - 08/2004
8	Acute malaria 01/2015 - 05/2002
8	Human Influenza (Influenza) 01/2014 - 09/2006
7	Cardiotoxicity 10/2022 - 01/2004
7	Cerebral Malaria 01/2017 - 11/2004
6	Leptospirosis 01/2020 - 11/2004
5	Vomiting 01/2022 - 12/2002
5	Anemia 12/2015 - 09/2005
4	Torsades de Pointes (Torsade de Pointes) 10/2022 - 01/2021
4	Hemolytic Anemia 06/2022 - 02/2014
4	Cardiac Arrhythmias (Arrythmia) 04/2021 - 11/2018
4	Bacterial Infections (Bacterial Infection) 01/2021 - 02/2005
4	Hypoxia (Hypoxemia) 03/2019 - 11/2009
4	Hemorrhage 01/2017 - 02/2002
4	Scrub Typhus (Typhus, Scrub) 07/2007 - 11/2004
4	Meningeal Tuberculosis (Tuberculous Meningitis) 03/2007 - 03/2004
3	Parasitic Diseases (Parasitic Disease) 01/2021 - 01/2012
3	Coinfection 12/2020 - 10/2004
3	Birth Weight (Birth Weights) 01/2020 - 03/2002
3	Shock 01/2019 - 09/2003
3	Neutropenia 01/2019 - 01/2004

Drug/Important Bio-Agent (IBA)

112	Antimalarials (Antimalarial Agents)IBA 01/2022 - 04/2002
102	artemisinin (artemisinine)IBA 04/2022 - 03/2002
86	ArtesunateIBA 01/2022 - 03/2002
70	Pharmaceutical PreparationsIBA 06/2022 - 04/2002
54	Primaquine FDA Link 06/2022 - 07/2003
50	artenimol (dihydroartemisinin)IBA 01/2022 - 04/2002
48	piperaquineIBA 01/2022 - 01/2004
42	Chloroquine (Aralen)FDA LinkGeneric 10/2022 - 03/2002
34	Quinine (Quinson)FDA Link 01/2020 - 03/2002
29	Mefloquine (Lariam)FDA LinkGeneric 10/2021 - 03/2002
26	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2022 - 10/2004
23	Anti-Bacterial Agents (Antibiotics)IBA 06/2022 - 07/2002
18	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 06/2022 - 04/2010
14	Amodiaquine (Camoquin)FDA Link 01/2022 - 01/2004
13	pyrimethamine drug combination fanasil (Fansidar)FDA Link 01/2022 - 05/2003
12	Lactic Acid (Lactate)FDA LinkGeneric 03/2019 - 03/2002
10	EnzymesIBA 03/2018 - 02/2002
10	Artemether FDA Link 01/2018 - 12/2003
9	Lumefantrine FDA Link 01/2021 - 06/2006
9	Proteins (Proteins, Gene)FDA Link 03/2016 - 04/2005
8	AntigensIBA 01/2022 - 03/2004
8	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 07/2021 - 01/2020
8	8-aminoquinolineIBA 01/2021 - 10/2011
8	ArtemisininsIBA 01/2019 - 04/2004
7	AcidsIBA 01/2019 - 08/2004
6	Azithromycin (Zithromax)FDA LinkGeneric 10/2022 - 01/2010
6	AntibodiesIBA 01/2022 - 07/2007
6	CytokinesIBA 01/2006 - 07/2002
5	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 06/2022 - 06/2005
5	VaccinesIBA 01/2022 - 11/2004
5	Antiviral Agents (Antivirals)IBA 01/2022 - 03/2003
5	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 07/2012
5	Biomarkers (Surrogate Marker)IBA 01/2017 - 02/2011
5	TabletsIBA 01/2017 - 01/2003
5	Oseltamivir (Tamiflu)FDA Link 01/2016 - 09/2006
5	proguanil drug combination atovaquone (malarone)FDA Link 09/2014 - 12/2002
5	Thiamine (Aneurin)FDA Link 07/2014 - 09/2003
5	Indicators and Reagents (Reagents)IBA 04/2013 - 08/2004
4	Dexamethasone (Maxidex)FDA LinkGeneric 07/2021 - 10/2004
4	quinolineIBA 01/2021 - 08/2007
4	Hemoglobins (Hemoglobin)IBA 01/2020 - 01/2017
4	Immunoglobulin G (IgG)IBA 01/2019 - 08/2004
4	CreatinineIBA 03/2018 - 08/2011
4	Doxycycline (Periostat)FDA LinkGeneric 07/2010 - 11/2004
4	ImmunosorbentsIBA 09/2005 - 02/2002
3	Oxidants (Oxidizing Agents)IBA 06/2022 - 01/2017
3	Ivermectin (Mectizan)FDA Link 01/2021 - 01/2020
3	Ofloxacin (Ofloxacine)FDA LinkGeneric 01/2021 - 03/2005
3	Amphotericin B (Amphotericin)FDA LinkGeneric 01/2021 - 05/2004
3	Fluconazole (Zonal)FDA LinkGeneric 01/2021 - 07/2002
3	hemozoinIBA 01/2020 - 02/2004
3	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA 01/2019 - 01/2002
3	Urea (Carbamide)FDA LinkGeneric 01/2019 - 08/2011
3	tafenoquineIBA 03/2018 - 02/2017
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2018 - 03/2004

Therapy/Procedure

63	Therapeutics 01/2022 - 07/2002
20	Mass Drug Administration 01/2022 - 01/2012
14	Aftercare (After-Treatment) 01/2019 - 07/2002
8	Chemoprevention 01/2022 - 03/2012
7	Insecticide-Treated Bednets 11/2018 - 09/2002
5	Resuscitation 01/2020 - 09/2005
4	Blood Transfusion (Blood Transfusions) 01/2021 - 11/2014
4	Prenatal Care (Care, Prenatal) 05/2015 - 11/2010